How can we improve a child's environment? How can we improve a child's environment? Content Editor: Dr Soundhar March 21, 2024 WHO News Section Child Health, Environmental health In an era where environmental pollution and climate change are increasingly affecting the health, development, and future of children, WHO and UNICEF have come up with a free online course to address these concerns. It aims to enhance the knowledge and resources of healthcare providers and reduce the risks effectively. Some of the key topics that are being addressed by this online course consist of the following: Air pollution, Climate change, Lead, and pesticide toxicity E-waste The online course provides comprehensive and in-depth knowledg e and exploration of children’s environmental health. It also addresses the health sector, where providers have limited knowledge to recognize, assess, and manage environment-related diseases. With this course, they aim to fulfill the right to safeguard the well-being of every child. Click here to read more

Need to strengthen hospital infection control practices Need to strengthen hospital infection control practices Content Editor: Dr. Sathya Prashaath March 2, 2024 Indian Journal of Medical Research Antimicrobial resistance, Hospital-acquired infections, Infections Antimicrobial resistance (AMR) is a major health threat in India, especially in hospitals, where infections caused by highly resistant bacteria are common and often fatal. Hospital epidemiology research is a key strategy to understand and prevent AMR infections in hospitals, by studying the sources, transmission, and prevention of these infections using advanced tools and methods. The training programme is a proposal to create a long-term institutional programme that trains junior clinicians in hospital epidemiology and infection prevention research, using the existing HAI surveillance network in India as a platform. There is a need to invest in interdisciplinary hospital infection prevention research training programmes, in partnership with international funding agencies, to address the AMR pandemic.

Public Health Daily News Snippets WHO Bulletin Releases Special Edition on Traditional Medicine Ahead of Global Summit The WHO Bulletin published its first special issue on traditional medicine since 1977, featuring research and policy analyses. This release precedes the 2nd WHO Global Summit on Traditional Medicine scheduled for December 2025 in New Delhi. Published on : Friday, November 28, 2025 Source : World Health Organization Global Health, Traditional Medicine Integration Read More Global Summit in Geneva Intensified Efforts to Curb Toxic Mercury Pollution A major international conference was held in Geneva from 3rd to 7th November 2025 to strengthen the global fight against mercury pollution . Delegates collaborated to accelerate the phase-out of this toxic metal from products and industrial processes, aiming to protect human health and the environment. Published on : Friday, November 28, 2025 Source : United Nations Environmental Health, International Policy Read More Fitness & Nation-Building: Insights from the National Fitness & Wellness Conclave 2025 The first-ever National Fitness & Wellness Conclave 2025 in Mumbai brought together policymakers, athletes, and industry leaders to reaffirm one message: India’s progress towards becoming a Viksit Bharat by 2047 depends on how seriously we take fitness today. With icons from sports and cinema joining the conversation, the conclave highlighted fitness as both a cultural shift and a public health necessity. Published on : Friday, November 28, 2025 Source : Press Information Bureau (PIB) Fit India Movement, Physical Activity, Non-Communicable Diseases, Viksit Bharat Read More Global Evidence Review of the Inequality- Pandemic Cycle: UNAIDS report The UNAIDS established the “Global Council on Inequality, AIDS and Pandemic ” in 2023. Its report “Breaking the inequality-pandemic cycle ” released in November 2025 is based on evidence from more than 1500 peer-reviewed literature and reports from government agencies and research institutions across multiple pandemics and its own empirical studies over the past 2 years. Published on : Friday, November 28, 2025 Source : Joint United Nations Programme on HIV/AIDS (UNAIDS), 2025 Pandemic preparedness, Social inequality, Global Health Read More Decomposition Analysis of Factors Driving Global Maternal Mortality Reduction A new Lancet Global Health paper highlights evidence that combining family planning with quality maternity services has driven a 41% global decline in maternal deaths since 2000. The study shows how contraception alone prevented more than 77,000 maternal deaths in 2023. Published on : Friday, November 28, 2025 Source : The Lancet Global Health Maternal Health, Reproductive & Sexual Health, Gender Equality, Family Planning, Declining Global Maternal Mortality Read More Delhi’s Air Quality Sees Noticeable Improvement: CAQM 2025 Report The 2025 update from the C ommission for A ir Q uality M anagement (CAQM ) highlights significant enhancements in Delhi's air quality and a marked reduction in stubble-burning incidents in nearby states. The report offers data-backed evidence of collaborative efforts to reduce pollution through the use of cleaner fuels, improved waste management, and more stringent regulatory measures. Published on : Tuesday, November 18, 2025 Source : Press Information Bureau, New Delhi Air Pollution, Environmental Health, Public Health Policy Read More Genomic Collaboration for a Safer Future: India and Italy Unite for Pandemic Preparedness The International Centre for Genetic Engineering and Biotechnology (ICGEB) round table in New Delhi emphasized the power of genomic research and collaboration in strengthening pandemic preparedness. Experts called for sustained global surveillance and rapid translation of genomic data to safeguard public health. Published on : Friday, November 14, 2025 Source : Press Information Bureau, New Delhi Genomic Surveillance, Pandemic Readiness Read More WHO Unveils Global Agenda to Strengthen Paediatric Clinical Trials The World Health Organization has unveiled a new global research agenda to close gaps in evidence on child health. It prioritizes equitable, high-impact paediatric trials to ensure that treatments for children are safe, effective, and grounded in sound science. Published on : Friday, November 14, 2025 Source : World Health Organization Health Research, Pediatric Health, Clinical Trials Read More WHO refutes Tylenol-Autism Link: Urges Evidence-Based Care A statement by the current US President, which linked Tylenol use during pregnancy to autism, prompted an immediate response from the World Health Organization. The WHO clarified that no scientific evidence supports this claim and urged reliance on medical guidance. Published on : Friday, November 14, 2025 Source : World Health Organization Maternal and Child Health, Health Communication, Global Health Governance Read More 2025 Lancet Countdown Report on Climate Change and Health Impacts of climate inaction have led to a 23% increase in heat-related deaths since the 1990s. Food insecurity affected 124 million more people due to extreme weather in 2023, with losses reaching $1.35 trillion. Addressing climate change has prevented 160,000 premature deaths from coal pollution and supported 16 million jobs in renewable energy. With COP30 ahead, WHO, along with member states, plans to emphasize climate action and a swift transition away from fossil fuels. Published on : Friday, November 7, 2025 Source : World Health Organization Climate change, food insecurity, Sustainability Read More WHO Introduces New Global Framework to Enhance National Health Emergency Response The World Health Organization has unveiled a new global guide, the National Health Emergency Alert and Response Framework, to bolster countries' readiness for health crises. Developed from lessons learned during the COVID-19 pandemic, it provides a standardized approach for managing emergencies. Published on : Friday, November 7, 2025 Source : World Health Organization Global Health Security, Emergency Preparedness Read More Training Modules to Strengthen Chemical Emergency Preparedness and Response in India The Ministry of Health and Family Welfare has introduced three specialized training modules to enhance India’s capacity for managing chemical emergencies. This initiative aims to build a skilled, coordinated response system across healthcare and disaster management sectors. Published on : Friday, November 7, 2025 Source : PIB Delhi Chemical Emergencies Preparedness, IHR, Disaster management Read More Daily News Snippets Monthly Archives 01-10 February, 2024 View More 14-20 January, 2024 View More 19-25th November, 2024 (26) View More 23-31stOctober, 2023 (18) View More 28-31 January, 2024 View More 7-13 January, 2024 View More 5-11th November, 2023 (5) View More 15-21st October, 2023 (12) View More 21-27 January, 2024 View More 26-30th November, 2024 (20) View More 01-04th November, 2023(4) View More 08-14th October, 2023 (5) View More March 27 - 31, 2023 (15) View More March 6 - 12, 2023 (24) View More February 23 - 25, 2023 (3) View More February 15 - 16, 2023 (8) View More March 20 - 25, 2023 (18) View More March 1 - 5, 2023 (8) View More February 20 - 22, 2023 (2) View More February 07 - 14, 2023 (5) View More March 13 - 18, 2023 (8) View More February 26 - 28, 2023 (15) View More February 17 - 19, 2023 (3) View More February 01 - 06, 2023 (5) View More Subscribe to get Latest Public Health Updates SUBSCRIBE

Air pollution impact assessment and initiatives to combat them. Content Editor: Dr. Aishwariya S January 10, 2024 at 1:30:00 PM Air Pollution, Public Health Country-wide study of Air pollution impacts on human health in 20 cities under the National Environment Health profile study was conducted. The following factors were assessed: Mercury levels exposure estimation. Air Quality Assessment. Impact of traffic emission and firecrackers amongst adolescents. Air quality impact on respiratory health due to crop burning. Effects of chronic exposure to biomass fuel smoke. Major steps taken by the Government to combat air pollution include: The National Clean Air Programme - A target reduction of 20-30% in particulate matter concentration by 2024, A city-based action plan and performance-based funding, A Public Grievance Redressal portal, and An emergency response system. 2. Measures for control of vehicular emissions- Leapfrogging from BS4 to BS6 fuel standards, Radiofrequency identity, Faster adoption and manufacture of electric vehicles, and Sustainable and affordable alternative transportation. 3. Control of industrial emissions: Notifications regarding So2 and NOx emission standards Ban on pet coke and furnace oil use 4. Air quality monitoring and network: National Air Quality Index (AQI) Ambient Air Quality Network Central Control Room for tracking PM concentrations Live Air Quality data Previous Next

Public Health Daily News Snippets WHO Bulletin Releases Special Edition on Traditional Medicine Ahead of Global Summit The WHO Bulletin published its first special issue on traditional medicine since 1977, featuring research and policy analyses. This release precedes the 2nd WHO Global Summit on Traditional Medicine scheduled for December 2025 in New Delhi. Published on : Friday, November 28, 2025 Source : World Health Organization Global Health, Traditional Medicine Integration Read More Global Summit in Geneva Intensified Efforts to Curb Toxic Mercury Pollution A major international conference was held in Geneva from 3rd to 7th November 2025 to strengthen the global fight against mercury pollution . Delegates collaborated to accelerate the phase-out of this toxic metal from products and industrial processes, aiming to protect human health and the environment. Published on : Friday, November 28, 2025 Source : United Nations Environmental Health, International Policy Read More Fitness & Nation-Building: Insights from the National Fitness & Wellness Conclave 2025 The first-ever National Fitness & Wellness Conclave 2025 in Mumbai brought together policymakers, athletes, and industry leaders to reaffirm one message: India’s progress towards becoming a Viksit Bharat by 2047 depends on how seriously we take fitness today. With icons from sports and cinema joining the conversation, the conclave highlighted fitness as both a cultural shift and a public health necessity. Published on : Friday, November 28, 2025 Source : Press Information Bureau (PIB) Fit India Movement, Physical Activity, Non-Communicable Diseases, Viksit Bharat Read More Global Evidence Review of the Inequality- Pandemic Cycle: UNAIDS report The UNAIDS established the “Global Council on Inequality, AIDS and Pandemic ” in 2023. Its report “Breaking the inequality-pandemic cycle ” released in November 2025 is based on evidence from more than 1500 peer-reviewed literature and reports from government agencies and research institutions across multiple pandemics and its own empirical studies over the past 2 years. Published on : Friday, November 28, 2025 Source : Joint United Nations Programme on HIV/AIDS (UNAIDS), 2025 Pandemic preparedness, Social inequality, Global Health Read More Decomposition Analysis of Factors Driving Global Maternal Mortality Reduction A new Lancet Global Health paper highlights evidence that combining family planning with quality maternity services has driven a 41% global decline in maternal deaths since 2000. The study shows how contraception alone prevented more than 77,000 maternal deaths in 2023. Published on : Friday, November 28, 2025 Source : The Lancet Global Health Maternal Health, Reproductive & Sexual Health, Gender Equality, Family Planning, Declining Global Maternal Mortality Read More Delhi’s Air Quality Sees Noticeable Improvement: CAQM 2025 Report The 2025 update from the C ommission for A ir Q uality M anagement (CAQM ) highlights significant enhancements in Delhi's air quality and a marked reduction in stubble-burning incidents in nearby states. The report offers data-backed evidence of collaborative efforts to reduce pollution through the use of cleaner fuels, improved waste management, and more stringent regulatory measures. Published on : Tuesday, November 18, 2025 Source : Press Information Bureau, New Delhi Air Pollution, Environmental Health, Public Health Policy Read More Genomic Collaboration for a Safer Future: India and Italy Unite for Pandemic Preparedness The International Centre for Genetic Engineering and Biotechnology (ICGEB) round table in New Delhi emphasized the power of genomic research and collaboration in strengthening pandemic preparedness. Experts called for sustained global surveillance and rapid translation of genomic data to safeguard public health. Published on : Friday, November 14, 2025 Source : Press Information Bureau, New Delhi Genomic Surveillance, Pandemic Readiness Read More WHO Unveils Global Agenda to Strengthen Paediatric Clinical Trials The World Health Organization has unveiled a new global research agenda to close gaps in evidence on child health. It prioritizes equitable, high-impact paediatric trials to ensure that treatments for children are safe, effective, and grounded in sound science. Published on : Friday, November 14, 2025 Source : World Health Organization Health Research, Pediatric Health, Clinical Trials Read More WHO refutes Tylenol-Autism Link: Urges Evidence-Based Care A statement by the current US President, which linked Tylenol use during pregnancy to autism, prompted an immediate response from the World Health Organization. The WHO clarified that no scientific evidence supports this claim and urged reliance on medical guidance. Published on : Friday, November 14, 2025 Source : World Health Organization Maternal and Child Health, Health Communication, Global Health Governance Read More 2025 Lancet Countdown Report on Climate Change and Health Impacts of climate inaction have led to a 23% increase in heat-related deaths since the 1990s. Food insecurity affected 124 million more people due to extreme weather in 2023, with losses reaching $1.35 trillion. Addressing climate change has prevented 160,000 premature deaths from coal pollution and supported 16 million jobs in renewable energy. With COP30 ahead, WHO, along with member states, plans to emphasize climate action and a swift transition away from fossil fuels. Published on : Friday, November 7, 2025 Source : World Health Organization Climate change, food insecurity, Sustainability Read More WHO Introduces New Global Framework to Enhance National Health Emergency Response The World Health Organization has unveiled a new global guide, the National Health Emergency Alert and Response Framework, to bolster countries' readiness for health crises. Developed from lessons learned during the COVID-19 pandemic, it provides a standardized approach for managing emergencies. Published on : Friday, November 7, 2025 Source : World Health Organization Global Health Security, Emergency Preparedness Read More Training Modules to Strengthen Chemical Emergency Preparedness and Response in India The Ministry of Health and Family Welfare has introduced three specialized training modules to enhance India’s capacity for managing chemical emergencies. This initiative aims to build a skilled, coordinated response system across healthcare and disaster management sectors. Published on : Friday, November 7, 2025 Source : PIB Delhi Chemical Emergencies Preparedness, IHR, Disaster management Read More Daily News Snippets Monthly Archives 01-10 February, 2024 View More 14-20 January, 2024 View More 19-25th November, 2024 (26) View More 23-31stOctober, 2023 (18) View More 28-31 January, 2024 View More 7-13 January, 2024 View More 5-11th November, 2023 (5) View More 15-21st October, 2023 (12) View More 21-27 January, 2024 View More 26-30th November, 2024 (20) View More 01-04th November, 2023(4) View More 08-14th October, 2023 (5) View More March 27 - 31, 2023 (15) View More March 6 - 12, 2023 (24) View More February 23 - 25, 2023 (3) View More February 15 - 16, 2023 (8) View More March 20 - 25, 2023 (18) View More March 1 - 5, 2023 (8) View More February 20 - 22, 2023 (2) View More February 07 - 14, 2023 (5) View More March 13 - 18, 2023 (8) View More February 26 - 28, 2023 (15) View More February 17 - 19, 2023 (3) View More February 01 - 06, 2023 (5) View More Subscribe to get Latest Public Health Updates SUBSCRIBE

Dog import rules for low-risk countries: Updates from CDC Content Editor: Dr. Chinmay August 7, 2024 at 2:00:00 PM Rabies, International Health, International Health Regulations Starting August 1, 2024, the CDC has simplified the process for bringing dogs into the U.S . from countries with low or no rabies risk . This change is intended to safeguard the health of both people and animals . Dogs from these countries can now enter with a CDC form, provided they are microchipped and over six months old. However, stricter regulations remain for dogs from high-risk areas, including additional documentation and vaccination requirements. Additionally, airlines have the option to request exceptions to these new rules. Click here to read more. Previous Next

Public Health Daily News Snippets WHO Bulletin Releases Special Edition on Traditional Medicine Ahead of Global Summit The WHO Bulletin published its first special issue on traditional medicine since 1977, featuring research and policy analyses. This release precedes the 2nd WHO Global Summit on Traditional Medicine scheduled for December 2025 in New Delhi. Published on : Friday, November 28, 2025 Source : World Health Organization Global Health, Traditional Medicine Integration Read More Global Summit in Geneva Intensified Efforts to Curb Toxic Mercury Pollution A major international conference was held in Geneva from 3rd to 7th November 2025 to strengthen the global fight against mercury pollution . Delegates collaborated to accelerate the phase-out of this toxic metal from products and industrial processes, aiming to protect human health and the environment. Published on : Friday, November 28, 2025 Source : United Nations Environmental Health, International Policy Read More Fitness & Nation-Building: Insights from the National Fitness & Wellness Conclave 2025 The first-ever National Fitness & Wellness Conclave 2025 in Mumbai brought together policymakers, athletes, and industry leaders to reaffirm one message: India’s progress towards becoming a Viksit Bharat by 2047 depends on how seriously we take fitness today. With icons from sports and cinema joining the conversation, the conclave highlighted fitness as both a cultural shift and a public health necessity. Published on : Friday, November 28, 2025 Source : Press Information Bureau (PIB) Fit India Movement, Physical Activity, Non-Communicable Diseases, Viksit Bharat Read More Global Evidence Review of the Inequality- Pandemic Cycle: UNAIDS report The UNAIDS established the “Global Council on Inequality, AIDS and Pandemic ” in 2023. Its report “Breaking the inequality-pandemic cycle ” released in November 2025 is based on evidence from more than 1500 peer-reviewed literature and reports from government agencies and research institutions across multiple pandemics and its own empirical studies over the past 2 years. Published on : Friday, November 28, 2025 Source : Joint United Nations Programme on HIV/AIDS (UNAIDS), 2025 Pandemic preparedness, Social inequality, Global Health Read More Decomposition Analysis of Factors Driving Global Maternal Mortality Reduction A new Lancet Global Health paper highlights evidence that combining family planning with quality maternity services has driven a 41% global decline in maternal deaths since 2000. The study shows how contraception alone prevented more than 77,000 maternal deaths in 2023. Published on : Friday, November 28, 2025 Source : The Lancet Global Health Maternal Health, Reproductive & Sexual Health, Gender Equality, Family Planning, Declining Global Maternal Mortality Read More Delhi’s Air Quality Sees Noticeable Improvement: CAQM 2025 Report The 2025 update from the C ommission for A ir Q uality M anagement (CAQM ) highlights significant enhancements in Delhi's air quality and a marked reduction in stubble-burning incidents in nearby states. The report offers data-backed evidence of collaborative efforts to reduce pollution through the use of cleaner fuels, improved waste management, and more stringent regulatory measures. Published on : Tuesday, November 18, 2025 Source : Press Information Bureau, New Delhi Air Pollution, Environmental Health, Public Health Policy Read More Genomic Collaboration for a Safer Future: India and Italy Unite for Pandemic Preparedness The International Centre for Genetic Engineering and Biotechnology (ICGEB) round table in New Delhi emphasized the power of genomic research and collaboration in strengthening pandemic preparedness. Experts called for sustained global surveillance and rapid translation of genomic data to safeguard public health. Published on : Friday, November 14, 2025 Source : Press Information Bureau, New Delhi Genomic Surveillance, Pandemic Readiness Read More WHO Unveils Global Agenda to Strengthen Paediatric Clinical Trials The World Health Organization has unveiled a new global research agenda to close gaps in evidence on child health. It prioritizes equitable, high-impact paediatric trials to ensure that treatments for children are safe, effective, and grounded in sound science. Published on : Friday, November 14, 2025 Source : World Health Organization Health Research, Pediatric Health, Clinical Trials Read More WHO refutes Tylenol-Autism Link: Urges Evidence-Based Care A statement by the current US President, which linked Tylenol use during pregnancy to autism, prompted an immediate response from the World Health Organization. The WHO clarified that no scientific evidence supports this claim and urged reliance on medical guidance. Published on : Friday, November 14, 2025 Source : World Health Organization Maternal and Child Health, Health Communication, Global Health Governance Read More 2025 Lancet Countdown Report on Climate Change and Health Impacts of climate inaction have led to a 23% increase in heat-related deaths since the 1990s. Food insecurity affected 124 million more people due to extreme weather in 2023, with losses reaching $1.35 trillion. Addressing climate change has prevented 160,000 premature deaths from coal pollution and supported 16 million jobs in renewable energy. With COP30 ahead, WHO, along with member states, plans to emphasize climate action and a swift transition away from fossil fuels. Published on : Friday, November 7, 2025 Source : World Health Organization Climate change, food insecurity, Sustainability Read More WHO Introduces New Global Framework to Enhance National Health Emergency Response The World Health Organization has unveiled a new global guide, the National Health Emergency Alert and Response Framework, to bolster countries' readiness for health crises. Developed from lessons learned during the COVID-19 pandemic, it provides a standardized approach for managing emergencies. Published on : Friday, November 7, 2025 Source : World Health Organization Global Health Security, Emergency Preparedness Read More Training Modules to Strengthen Chemical Emergency Preparedness and Response in India The Ministry of Health and Family Welfare has introduced three specialized training modules to enhance India’s capacity for managing chemical emergencies. This initiative aims to build a skilled, coordinated response system across healthcare and disaster management sectors. Published on : Friday, November 7, 2025 Source : PIB Delhi Chemical Emergencies Preparedness, IHR, Disaster management Read More Daily News Snippets Monthly Archives 01-10 February, 2024 View More 14-20 January, 2024 View More 19-25th November, 2024 (26) View More 23-31stOctober, 2023 (18) View More 28-31 January, 2024 View More 7-13 January, 2024 View More 5-11th November, 2023 (5) View More 15-21st October, 2023 (12) View More 21-27 January, 2024 View More 26-30th November, 2024 (20) View More 01-04th November, 2023(4) View More 08-14th October, 2023 (5) View More March 27 - 31, 2023 (15) View More March 6 - 12, 2023 (24) View More February 23 - 25, 2023 (3) View More February 15 - 16, 2023 (8) View More March 20 - 25, 2023 (18) View More March 1 - 5, 2023 (8) View More February 20 - 22, 2023 (2) View More February 07 - 14, 2023 (5) View More March 13 - 18, 2023 (8) View More February 26 - 28, 2023 (15) View More February 17 - 19, 2023 (3) View More February 01 - 06, 2023 (5) View More Subscribe to get Latest Public Health Updates SUBSCRIBE

Rabies on the rise in Andhra Pradesh reports IDSP Content Editor: Dr. Himabindu Reddy August 4, 2023 at 12:30:00 PM One health, Rabies, Public health According to D. Mohana Krishna, Joint Director of the Integrated Disease Surveillance Programme, the State of Andhra Pradesh has reported 12 rabies-related deaths in the last six months and 27 in the last 18 months. During the Lok Sabha discussion of this issue, Satya Pal Singh Baghel, the Union Minister of State for Health and Family Welfare responded that out of 269 rabies death nationwide in 2022, 29 were from Andhra Pradesh. The rise in cases despite the adequate supply of anti-rabies vaccines, and stray dogs control programs calls for the attention of health officials. To reduce Rabies incidence and prevalence, the Central government launched the National Action Plan For Dog Mediated Rabies Elimination (NAPRE) from India by 2030 . Previous Next

ICMR calls for companies to develop typhoid and paratyphoid vaccines. Content Editor: Dr Manu March 22, 2025 at 2:16:07 PM Vaccine Development, ICMR, Vaccine Trial, Typhoid Vaccine A study found a national incidence of around 360 typhoid cases per 100,000 people, translating to approximately 4.5 million cases annually. The Indian Council of Medical Research (ICMR) released an Expression of Interest (EoI) for companies to help validate and commercialise a new vaccine candidate developed by the National Institute for Research in Bacterial Infections (ICMR-NIRBI), Kolkata (erstwhile ICMR-NICED) that may help tackle enteric fever caused by both Salmonella typhi and S. paratyphi A . Key features of the technology include: Isolation and Characterization of OMVs: Outer Membrane Vesicles (OMVs) were isolated from Salmonella Typhi and Salmonella Paratyphi A. These OMVs were comprehensively characterized to identify associated antigens, such as lipopolysaccharide (LPS) and Vi-polysaccharide. Immunization and Immune Response: Adult mice were immunized orally with three doses of the bivalent OMV-based immunogen (25 μg/200 μl). The immunization induced robust humoral responses, including significant serum IgG levels against LPS and Vi-polysaccharide. It activated specific immune cell populations, such as CD4+, CD8+, and CD19+ cells, in the spleen of immunized mice. The vaccine also stimulated Th1 and Th17 cell-mediated immune responses. Protective Efficacy: Immunization with the bivalent OMVs provided protection against systemic infection caused by lethal doses of heterologous Salmonella strains in adult mice models. The protective effect was found to be mediated by a combination of humoral and cell-mediated immune responses. Novel Mechanism of Protection: Anti-OMVs antibodies generated through immunization significantly inhibited bacterial motility and their ability to penetrate mucin layers. This new candidate vaccine is considered superior to the current typhoid conjugate and Vi-polysaccharide based vaccines, as the latter only protect against enteric fever caused by S. typhi strains. The EoI now calls for companies to partner with ICMR on validating these results through vaccine trials and help develop and commercialise vaccines for use. ICMR will provide funding and technical support through expert guidance for the same. Previous Next

Mapping asthma hot spots: Uncovering urban trends and pandemic impacts in New York State Content Editor: Dr Ghurumourthy October 3, 2024 at 3:30:00 PM Epidemiology, Chronic Respiratory Diseases, Asthma Asthma, a chronic lung condition, can be managed through proper clinical care and self-management. The New York State Department of Health analyzed asthma-related emergency department (ED) visits from 2016 to 2022 using Esri’s Emerging Hot Spot Analysis. The study revealed urban areas like Buffalo, Rochester, and NYC had significant asthma hot spots , with ED rates decreasing during the pandemic compared to pre-pandemic levels. While many persistent hot spots became sporadic, some areas in NYC, particularly in the Bronx and Manhattan, saw intensifying hot spots. This method enhances traditional mapping by identifying emerging geographic patterns and can be used to evaluate the impact of local-level interventions for asthma and other chronic conditions. Click here to read more. Previous Next