Update: Southeast Asia Faces a Surge in COVID-19 Linked to JN.1 Subvariant
Content Editor: Dr. Jahnvi Saboo
May 31, 2025 at 12:56:48 PM
COVID-19, Infectious disease outbreaks, Global Healt

COVID-19 cases rose in several Southeast Asian countries in April-May, driven by JN.1 subvariants (LF.7, NB.1.8), probably due to periodic waves and waning immunity. Authorities are monitoring the situation closely.
Singapore:
Between April 27 and May 3, fresh COVID-19 cases surged to 14,200, up from 11,100 in the preceding week.
This marks the first time the nation’s government has released data on COVID-19 case numbers - an action usually undertaken only in concerning situations.
Thailand:
Reports a significant spike. Gatherings held for the Songkran festival may have contributed to enhanced transmission.
Almost 70% of cases are associated with the JN.1 sub variants, followed by the previously dominant XEC variant accounts
49,065 new COVID-19 cases were reported between May 11-17. This number rose to almost 65,000 new cases between May 18 and 24.
According to experts, the peak is yet to come.
Hong Kong and Mainland China
Also experienced an uptick in cases around mid-April and early May.
According to surveillance data from May 3-10, Hong Kong’s Centre for Health Protection noted that COVID-19 positivity rates in respiratory samples hit a one-year high.
On May 23, the authority reported early signs of slow down in transmission, but urged citizens to continue to stay vigilant.
The China CDC also reported that test positivity rates more than doubled in these 5 weeks. China experienced a similar trend last summer.
Taiwan:
Cases surged by 88% during the week of May 11-17 compared to the prior week.
The Taiwanese CDC predicts the cases to peak around mid-late June at about 55,000-60,000, which is half of what the country witnessed at the same time last year.
India:
No significant rise so far.
Also witnessing a gradual increase. As of May 27, the country had 1010 active cases.
Kerala accounts for a majority of cases followed by Maharashtra, Telangana, Delhi.
Authorities are reviewing preparedness measures and are deploying additional resources to ensure the health systems’ ability to respond to the ongoing outbreak.
Variants responsible for this outbreak:
LF.7 and NB.1.8. Both have evolved from JN.1—the variant used in developing the current COVID-19 vaccine formulation
The XEC variant was previously dominant in the Southeast Asia region but is now being replaced by JN.1 descendants which are more transmissible.
These variants are unlikely to be more lethal. Hospitalizations and deaths remain in line with expected rates for the current case numbers.
Causes of rise in case numbers:
Periodic waves of increase in case numbers, as is observed with most endemic respiratory diseases.
Waning population immunity.
Response across the region:
Increased international, national and subnational surveillance.
Efforts to increase immunization coverage.
Test kits, Vaccine supplies and capacities of healthcare facilities are being enhanced.
Notably, the Thai government has made provisions that allow its COVID-19 infected citizens to get free online consultations via three partner applications.
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