• Sentinel Enhanced Dengue Surveillance System (SEDSS) conducts enhanced surveillance for dengue and dengue-like acute febrile illnesses in Puerto Rico.

• This data is from the report from May 2012 to December 2022, which was collected from five healthcare facilities of Puerto Rico..

• Patients who had fever within the past 7 days during data collection & patients who had either rash and conjunctivitis, rash, arthralgia, or fever were enrolled in the study.

• Specimens collected during enrollment were  blood, urine, nasopharyngeal, and oropharyngeal specimens. 

• Diagnostic testing was done for dengue stereotypes 1-4, chikungunya virus, Zika virus, influenza A and B, SARS- CoV-2, and 5 other respiratory illnesses.

• The epidemic curves of three arboviruses indicate dengue is endemic, outbreaks of chikungunya and Zika were sporadic with peak in case count in late 2014 and 2016.

• Report described fluctuation in incidence and the value of active surveillance, testing for panels of acute respiratory viruses and flexible and responsive surveillance systems in addressing public health challenges.

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