• The multi-country cholera outbreak report, as of May 2024, details a significant surge in new cases, with 46,364 reported in May alone, a 58% increase from the previous month across 19 countries.

• However, the death toll decreased by 37%, with 185 deaths in May.

• The Eastern Mediterranean region reported the highest cases, followed by Africa,  America, Southeast Asia, and Europe.

• The WHO has classified the outbreak as a Grade 3 emergency due to its widespread and persistent nature.

• Mitigation efforts include deploying 18 experts and ongoing regional and country-level support.

• WHO has revised public health surveillance guidance and promoted laboratory strengthening.

• Despite requests for 19 million vaccine doses, constrained supply has limited preventive campaigns.

• Technical support and training are provided for case management, infection prevention, control, water, sanitation, and hygiene (WASH).

• Challenges impacting the response include the effects of natural disasters, climate change, data quality inconsistencies, insufficient vaccine stocks, and overstretched response capacities.

• There's an increased risk of cross-border transmission, necessitating continued efforts for long-term solutions to reduce the cholera burden.

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