Marburg Virus outbreak in Africa - High Case Fatality
Content Editor: Dr. Siddharth Singh
April 3, 2023 at 4:04:22 PM
Global Health, Outbreak

Marburg Virus outbreak in Equatorial Guinea and Tanzania, the first ever outbreak of the disease in the countries. WHO estimated "very high" risk of spread of disease.
The countries are responding to the outbreak through contact tracing and restricting movements.
Marburg Virus, first identified in 1967 in Germany during outbreaks in Germany and Serbia. It causes severe and fatal viral hemorrhagic fevers. It is closely related to Ebola and is rated as "High Risk" pathogen by the WHO.
It spreads to humans through contact with fruits bats and further human to human transmission through direct contact with bodily fluids of patients or contaminated surface, similar to Ebola. There has been previous outbreaks of the Virus.
Notably, 1975, 2021, 2022, and 2023 within African countries being most affected and often with high fatalities. There is no approved vaccines, antiviral or monoclonal antibodies for the Virus.
Case detection through contact tracing, molecular diagnosis, and quarantine is central to managing the spread of disease. With recent outbreaks in different parts of the world, the concept of "One Health" is increasingly taking center stage.
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