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Ixchiq - The first vaccine approved for Chikungunya virus

Content Editor: Dr Urmimala Maiti

November 22, 2023 at 12:30:00 PM

Vaccination, Chikungunya, Clinical Trial, Vector-borne diseases

Content Editor: Dr Urmimala Maiti
  • The US FDA approved Ixchiq as the first vaccine against the Chikungunya virus for the 18-year-old and above age group.

  • Chikungunya is endemic in tropical and subtropical regions of Africa, Southeast Asia, and America.

  • Its threat is not only restricted to the acute symptoms but also to the chronic debilitating complications and fatal infection in newborns following mother-to-child transmission.

  • The FDA approved the vaccine using the Accelerated Approval pathway based on Phase III clinical trial data.

  • Six months after vaccination, the live-attenuated, single-dose vaccine demonstrated 96.3% seropositivity.

  • The trial reported severe adverse reactions in some participants.

  • It awaits a postmarketing trial to determine the seriousness of the reactions.

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