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Is there any association between sperm defects after COVID-19 infection?

Content Editor: Dr. Soundhar

May 3, 2024 at 3:30:00 PM

Post-COVID, COVID-19, Public Health

Content Editor: Dr. Soundhar
  • Researchers tracked semen quality for 109 days in 58 men after the diagnosis of COVID-19, for which they used a linear mixed effects model to analyze at different time points before and after infection.

  • They noted that SARS-CoV-2 entry into testicular cells leads to testes injury and impairs sperm production, which is facilitated by angiotensin-converting enzyme 2.

  • Even though there was not much difference in volume, median total count, concentration, and motility were lower, and the percentage of non-moving sperm was also higher.

  • Also, sperm survival and normal form decreased, with more defects in the head.

  • The greatest defect occurred within 30 days, followed by recovery and return to normal by 90 days.

  • A significant decline was noted in moderate to high fever cases.

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