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Is azithromycin a cost-effective method of reducing sepsis during delivery?

Content Editor: Dr. Manu Goel

March 8, 2024 at 2:00:00 PM

Anti-Microbial Resistance, Reproductive and Maternal Health, Communicable diseases

Content Editor: Dr. Manu Goel
  • Building on the results of the Azithromycin Prevention in Labour Use Study (A-Plus), a study found that providing pregnant women delivering vaginally with an oral dose of azithromycin is an economical approach to lower the risk of infection, sepsis, and mortality in the mother.

  • For 91 cents per pregnancy, the study showed that this intervention averted 249 maternal hospitalizations, and 1592 incidents of maternal sepsis, infection, and mortality.

  • $32,661 was saved overall for every 100,000 pregnancies.

  • According to the primary author, this can assist ministries in low and middle-income countries (LMICs), which have twice the prevalence of chronic diseases as affluent countries, in cost-effectively allocating their limited resources.

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