The non-sugar sweetener aspartame has been linked to adverse health outcomes, according to the Indian Council of Medical Research (ICMR).

IARC and the WHO-FAO Joint Expert Committee on Food Additives (JECFA) jointly evaluated it.

According to the report, there is "limited evidence" of possible human carcinogenicity.

Aspartame is classified by the IARC as "potentially carcinogenic" to humans (IARC Group 2B), and the JECFA has reiterated that 40 mg/kg of body weight is the safe daily intake.

The Food Safety and Standards Authority of India (FSSAI) has set guidelines for artificial sweeteners in line with risk assessments and ADI established by JECFA, aligned with Codex Alimentarius Commission standards.