Lancet in a recently published RCT finds that higher dose corticosteroids are linked to 60% increased risk of death in hospitalized COVID-19 patients requiring low oxygen. 

In the study, the high dose group had more non-COVID pneumonia and hyperglycemia requiring more insulin than the usual-care patients. 

The RECOVERY collaborative Group researchers, the author of the current papers have already established that low-dose corticosteroids reduces deaths among COVID-19 patients who require oxygen. 

This comes in light among many such events where millions lost their life especially in the second wave of COVID-19 where the free flow of steroids was speculated as one of the causes of excess mortality. 

The article has many more facades to encounter in coming times.