• A cluster-randomized controlled trial in Chandigarh, India, aimed to reduce chronic disease risk factors in adolescents through a school-based health-promotion intervention was conducted.

• Twelve public schools were randomized into intervention and control groups, involving eighth-std students (n = 453), parents (n = 395), and teachers (n = 94).

• Using the Precede-Proceed Model, the intervention included classroom and physical activity sessions for adolescents, parents, and teachers separately.

• Among adolescents, the intervention reduced salt intake and alcohol use, and increased fruit consumption and physical activity.

• No significant effects were observed on sugar and vegetable intake or tobacco use.

• Exploratory findings showed positive changes in parents' and teachers' behaviors, indicating the effectiveness of involving the broader school community in behavior-change interventions.

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