• A study using data from the Medical Monitoring Project (MMP) between 2017 and 2022 assessed quality of life (QoL) indicators among U.S. people living with HIV (PWH) aged ≥50 years. 

• The study focused on five QoL indicators set by the National HIV/AIDS Strategy (NHAS) for 2025: self-rated health, access to mental health services, unemployment, food insecurity, and housing stability.

• Despite advances in HIV treatment, minimal progress was observed across most indicators. 

• In 2022, only 65% of PWH aged ≥50 years reported good or better health, falling short of the 95% goal.

• Unmet need for mental health services rose to 21.5%, while unemployment decreased slightly from 11.7% to 8%. 

• Hunger or food insecurity improved, particularly for those aged ≥65 years, meeting the 2025 target.

• However, housing instability remained a significant issue, with 12.5% of older PWH experiencing unstable housing, far from the 7.4% goal.

• The findings highlight the need for tailored interventions, focusing on mental health services, employment support, and housing stability to meet the NHAS 2025 goals. 

• Multisectoral approaches and continued monitoring are essential to improving the overall QoL for older PWH.

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