• Mycobacterium abscessus subspecies massiliense infections associated with stem cell treatment clinics in Mexico.

• In late 2022, three patients from Arizona and Colorado developed serious infections after receiving donor embryonic stem cell injections for various conditions, including multiple sclerosis, psoriatic arthritis, and osteoarthritis.

• Whole genome sequencing and phylogenetic analysis identified clonal isolates, indicating a common source of infection likely related to stem cell procedures.

• Public health agencies in Colorado and Arizona are investigating these cases, highlighting the significant risks associated with medical tourism for treatments not approved by the FDA.

• The report underscores the need for vigilance and proper guidance for individuals considering medical procedures abroad to prevent similar outbreaks in the future.

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