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05. Why India needs to scale up the pace of its genome sequencing?

December 28, 2022 at 1:28:48 PM

COVID-19 preparedness

  • Based on 30 genome sequences deposited between October and December and 14 genome sequences in December alone from China and the BF.7 appears to be the dominant variant. 

  • The BF.7 sub-lineage with three additional immune escape mutations already seen in other variants has been found in some people arriving from China; these mutations may increase transmissibility further but will not increase disease severity.

  • In fact, given that a large percentage of the population enjoys hybrid immunity from vaccination and natural infection leading to all Omicron sub-lineages causing only a mild disease, the focus in India should be on any increase in hospitalisations, particularly ICU admissions.

  • It is therefore, vital to ramp up genome sequencing (and not increase testing) to track new variants as the virus evolves by accumulating mutations.

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