The 2022 update in strategies to prevent Surgical Site Infections(SSIs) in acute care hospitals was released recently stating, 'Antibiotic prophylaxis can be discontinued at the time of surgical closure in the operating room'. 

Antibiotic administration post-incision closure does not warrant reducing SSIs instead leads to Clostridioides difficile infection, antibiotic resistance, and acute kidney injury.

A few of the 19 essential practices to reduce SSIs are:

Administration of antibiotics within 1 hour prior to incision. 

Use a combination of parenteral and oral antimicrobial prophylaxis prior to colorectal surgery.

Decolonize surgical patients with an anti-staphylococcal agent preoperatively for cardiothoracic and orthopedic procedures.